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IPS Conference 2006
Abstracts

Abstract # 73:

Scheduled for Tuesday, June 27, 2006 11:40 AM-12:00 PM: Session 12 (Kama A) Symposium
   


CYNOMOLGUS (MACACA FASCICULARIS) BEHAVIOUR AND STRESS IN SEMI-WILD CONDITIONS, GANG CAGES, PAIR CAGES AND SINGLE CAGES

A. Fernstrom1,2, Y. Paramastri3, K. Westlund4, H. Carlsson2, D. Sajuthi3, J. Pamungkas3, S. J. Schapiro5 and J. Hau1,2
1Department of Experimental Medicine, University of Copenhagen and State Hospital, Copenhagen, Denmark, 2Uppsala University, 3Primate Research Centre, Bogor Agricultural University, 4Swedish Institute for Infectious Disease Control, 5University of Texas MD Anderson Cancer Center
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     Cynomolgus monkeys (Macaca fascicularis) are used extensively in biomedical research. They are imported from tropical source countries to Europe and the US in significant numbers. A comparative analysis of the behaviour, and stress indicators, of cynomolgus monkeys housed under different conditions in Indonesia and Sweden is underway, to determine how much variation exists between populations. Studies were conducted on Tinjil Island, where cynomolgus monkeys live in semi-wild conditions, and the results compared with the behaviour of animals housed in different cage types, focusing on single- and pair-cages in Bogor, Indonesia and at the Swedish Institute for Infectious Disease Control in Stockholm. In addition, fecal excretion of relevant glucocorticosteroids and immunoglobulin A (IgA) was quantified as measures of acute and chronic stress, respectively. The implications of differences between populations, and between different housing conditions, for the validity of scientific output will be discussed.

Modified: 18 December 2005



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