Abstract # 13130 Event # 163:

Scheduled for Saturday, August 11, 2018 10:15 AM-10:30 AM: (Chula Vista ) Oral Presentation



C. K. Lutz1, M. T. Menard2, J. S. Meyer2 and M. A. Novak2
1Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX 78245-0549, USA, 2University of Massachusetts, Amherst, MA

Alopecia occurs both in human and nonhuman primates. Although alopecia is often presented as a welfare issue in nonhuman primates, it is a complex condition with a number of possible causes. The purpose of this study was to assess the impact of pregnancy and stress on alopecia in rhesus monkeys. The subjects were 113 socially-housed adult female rhesus macaques of which 27 were pregnant, 35 were nursing infants, and 51 were controls. During routine physicals, photographs were taken for assessment of alopecia, and hair was shaved from the back of the neck and assayed for hair cortisol. Weight, a weight x age interaction, and age of infant (nursing females) had limited contributions to the expression of alopecia, but there was no association between hair cortisol and alopecia. However, there was a significant effect of pregnancy (Χ2(2)=9.291, P<0.05). Alopecia was more prevalent in pregnant than control females (Χ2(1)=9.296, P<0.005), but there was no difference between nursing and control females. Pregnancy was also associated with hair cortisol (F(2,110)=25.827, P<0.001). Nursing females had higher hair cortisol levels than pregnant (P<0.05) and control (P<0.001) females, and pregnant females had higher levels of hair cortisol than control females (P<0.005). Although alopecia does not appear to be associated with hair cortisol in female rhesus macaques at this facility, both alopecia and hair cortisol are associated with pregnancy. Supported by P51OD011133, R24OD01180-15.