Abstract # 13287 Event # 117:

Scheduled for Friday, August 23, 2019 10:30 AM-10:45 AM: (Wisconsin Historical Society Auditorium) Symposium


UNDERSTANDING REPRODUCTIVE PROCESSES THROUGH HORMONE PANEL ANALYSIS

D. W. Erikson
Oregon National Primate Research Center, Endocrine Technologies Core, Beaverton, OR 97006, USA
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     Advancing knowledge of reproductive processes and fetal/neonatal development is critical in order to ensure optimal maternal and fetal health, and to improve or control fertility. Interdisciplinary research is needed to understand these processes, and to improve the diagnosis and treatment of reproductive disorders. In addition, unintended pregnancy rates have remained high over the last three decades, due in part to lack of access to contraceptives, as well as non-compliance and non-use of contraception. These reproductive health issues impact quality of life, and further advances in understanding these issues through state-of-the-art research are needed to improve maternal-fetal and neonatal health. The Endocrine Technologies Core (ETC) at Oregon National Primate Research Center (ONPRC) offers assay platforms to help advance research directed at better understanding reproductive processes and associated health issues. Using state-of-the-art platforms such as automatic immunoassay and liquid chromatography-tandem mass spectrometry we are able to measure targeted panels of endogenous steroid hormones and synthetic contraceptive hormones in humans and nonhuman primates, while traditional platforms such as radioimmunoassay and ELISA allow us to measure proteins and gonadotropins. Through this combination of technologies the ETC offers a wide variety of assay services to measure hormones in translational models of reproductive disorders. This presentation will focus on how these assay technologies are applied to research projects at ONPRC and other collaborating institutions. Supported by NIH P51OD011092.