Abstract # 13457 Event # 198:

Scheduled for Saturday, August 24, 2019 01:15 PM-01:30 PM: (Room 313) Symposium


SEASONAL VARIATION OF MICROBIOTA AND METABOLOME IN FECAL SAMPLES OF CAPTIVE AND WILD GOLDEN SNUB-NOSED MONKEYS (RHINOPITHECUS ROXELLANAE)

Y. Zeng1, X. NI1, D. ZENG1, L. NIU2, J. DENG2, W. ZHENG3, Y. FAN4, Y. LI1 and L. KAN3
1Sichuan Agricultural University, College of Veterinary Medicine, Ya'an City, Sichuan, USA, 2Chengdu Wildlife Institute, 3Sichuan Tangjiahe National Nature Reserve, 4Cangxi National Forest Park Administration
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The metabolic activity of the mammalian gut microbiota plays a crucial role in the digestion and absorption of host nutrients. This is particularly true for primates such as the golden snub-nosed monkey (Rhinopithecus roxellanae), a folivorous primate with marked seasonal dietary variation. However, the metabolic activity of the golden monkey gut microbiota remains unknown. Here, we examined the composition and function of the fecal microbiota of wild and captive golden monkeys across seasons by using 16S rRNA amplicon sequencing, metagenomics, and metabolomics. We observed significant seasonal variation of microbiota and metabolites. For example, in autumn and winter, Firmicutes, Verrucomicrobia, and Rumiococcaceae were in higher abundance in wild individuals. In spring and summer, Gammaproteobacteria dominated in captive individuals. Additionally, acetate and glucose were important metabolites in the wild individuals in summer. Notably, glutamate, a major metabolite involved in the metabolism of D-Glutamine and D-glutamate, was obtained from captive monkeys in winter. These data indicate that there are more beneficial microbiome and metabolites found in wild golden monkeys with seasonal differences. Therefore, we need to improve the dietary composition of captive golden monkeys based on nutritional requirements.