Abstract # 2790 Event # 61:

Scheduled for Friday, June 18, 2010 10:15 AM-10:40 AM: Session 12 (Medallion Ballroom A/B) Symposium


S. J. Schapiro
The University of Texas M. D. Anderson Cancer Center, The Michale E. Keeling Center for Comparative Medicine and Research, Department of Veterinary Sciences, 650 Cool Water Dr., Bastrop, TX 78602, USA
     In captive research environments for nonhuman primates (NHP), social housing strategies are often in conflict with protocols designed to minimize disease transmission. This is particularly true in breeding colonies, and is especially relevant when attempting to establish a colony of specific pathogen free (SPF) animals from a conventional population of primates. Numerous strategies have been used to establish SPF breeding colonies (primarily of macaques), ranging from nursery rearing of neonates to single housing of socially-reared yearlings to the rearing of infants in large social groups. All of these strategies attempt to balance the effects of the chosen socialization strategy on the ultimate elimination of the target pathogens. While the primary areas of concern are typically NHP-to-NHP socialization and disease transmission, socialization and disease transmission between humans and NHP are also concerns. This results in numerous regulations and substantial requirements for Personal Protective Equipment when working with some species, to address potentially serious, yet very small risks. This process may increase the risk of less serious accidents. The disease states of NHP breeding colonies may also be affected by selective breeding processes, either by creating subpopulations of animals that do not have target diseases (SPF) or by creating situations in which the best (least diseased) animals are sold and the breeding colony is stocked by animals that may be more disease-susceptible than those that were sold.