Abstract # 2919 Event # 9:

Scheduled for Thursday, June 17, 2010 11:00 AM-11:10 AM: Session 2 (Medallion Ballroom A) Oral Presentation


S. J. Schapiro, L. E. Williams, S. P. Lambeth, B. N. Nehete and P. N. Nehete
UTMDACC, Michale E. Keeling Center for Comparative Medicine, DVS, 650 Cool Water Dr., Bastrop, TX 78602, USA

Nonhuman primates are occasionally transported between facilities and/or locations as part of their use in research. Such transportation episodes are thought to affect a variety of behavioral and physiological parameters, although few quantitative studies exist that support this supposition. Additionally, it is difficult to determine when transported primates have acclimated to their new environment. Approximately 75 chimpanzees were transported by truck from the Primate Foundation of Arizona to the Michale E. Keeling Center for Comparative Medicine and Research in Bastrop, TX. Blood samples were collected for hematological, chemistry, and immunological analyses (1) immediately prior to transport, (2) immediately upon arrival in Texas, and (3) at various time points after arrival. Analyses revealed statistically significant differences in numerous physiological and immunological parameters as a function of the approximately 24-hour transport episode, with values eventually returning to pre-transport levels after varying time periods at the Keeling Center. While many of these changes appeared to indicate that the transportation process was stressful for the animals, not all did. These data (1) confirm that moving chimpanzees between facilities affects both physiological and immunological responses and (2) suggest that transported animals must be provided with a sufficient period of time to acclimate to a new environment prior to beginning any research projects, especially protocols that involve the measurement of immunological parameters.