Abstract # 2947 Event # 16:

Scheduled for Thursday, June 17, 2010 10:30 AM-10:40 AM: Session 5 (Medallion Ballroom B) Oral Presentation


THE DEVELOPMENT OF OBESITY BEGINS AT AN EARLY AGE IN CAPTIVE COMMON MARMOSETS (CALLITHRIX JACCHUS).

M. L. Power1,2,3, C. N. Ross3,4 and S. D. Tardif3,4
1Smithsonian National Zoological Park, Nutrition Laboratory, Conservation Ecology Center, Washington , DC 20008, USA, 2American College of Obstetricians and Gynecologists, 3Southwest Foundation for Biological Research, 4University of Texas Health Science Center, San Antonio
line
     

In this study we investigated the development of adiposity in captive common marmosets (Callithrix jacchus) from birth through 6 months. We report data on lean and fat mass for 18 marmosets, 8 considered to be lean and 10 considered to be fat (>15% body fat) at 6 months. Infants were weighed within 48 hours of birth (Day 1 wt), and at 1, 2, 3 and 6 months; body fat was estimated by quantitative magnetic resonance at 1, 2 and 6 months. Mean Day 1 wt was 31g and did not differ between groups. At 6 months juveniles classified as fat had greater lean mass [215g vs 171g, F(1,14)=24.177, P<0.001] as well as fat mass [64g vs 19g, F(1,14)=85.637, P<0.001]. The relative gain in fat compared to lean mass was greater in fat subjects [0.319 vs 0.078, F(1,14)=117.7, P<0.001]. The relationship between fat and lean mass changed between 1 and 6 months; in lean subjects it decreased while in fat subjects it increased. By 2 months fat-to-lean mass was significantly greater in fat subjects [F(1,13)=6.72, P=0.022]. Interestingly, Day 1 wt was associated with the gain in fat mass from 1 to 6 months in fat subjects [r=0.857, P=0.007]; but not in lean subjects [r=0.485, P=0.223]. Excess adiposity in captive marmosets appears to develop by 2 months of age, and may be affected by birth weight.