Abstract # 3178 Event # 24:

Scheduled for Saturday, September 17, 2011 11:00 AM-11:15 AM: Session 6 (Meeting Room 410) Oral Presentation


EFFECTS OF DESENSITIZATION PROGRAM ON IMPORTED CYNOMOLGUS MACAQUES (MACACA FASCICULARIS)

S. L. Hastings and D. M. Abney
Charles River Laboratories, 6995 Longley Lane, Reno, NV 89521, USA
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It has been suggested that desensitizing animals to study stimuli helps reduce stress during study procedures. At Charles River Laboratories (Sparks, NV), all nonhuman primates arriving from breeding facilities in China undergo a required four week import quarantine period in which they receive desensitization training to three study-specific stimuli. For this study, subjects were chosen from two separate shipments (Group 1 and Group 2) and each group consisted of 17 males and 17 females (n = 68). Group 1 was desensitized to leather catch gloves, a transfer box, and the false cage back three times a week. Group 2 was not desensitized to any study stimuli. After the quarantine period was complete, the animals were tested on two separate occasions to determine how long it took them to enter a transfer box and to be hand-caught with catch gloves. We found that Group 1 took significantly less time to enter the transfer box on both occasions [T- test: P<0.005, P<0.05]. However, when tested on hand-catching, we found Group 2 took significantly less time than Group 1 [T-test: P<0.0001]. When tested the second time, there was no significant difference in times between the groups. This data suggests that the desensitization plan for the transfer box is successful, but additional desensitization may be needed for the catch gloves.