Abstract # 4296 Poster # 144:

Scheduled for Friday, June 22, 2012 07:00 PM-09:00 PM: Session 22 (Gardenia) Poster Presentation


A FUNCTIONAL IMAGING STUDY OF “JEALOUSY” IN CAPTIVE MALE TITI MONKEYS (CALLICEBUS CUPREUS)

N. Maninger1, S. P. Mendoza1,2, T. J. Schaefer1, W. A. Mason1,2, S. R. Cherry1,3 and K. L. Bales1,2
1California National Primate Research Center, University of California, Davis, CA 95616, USA, 2Psychology Department, University of California, Davis, 3Center for Molecular and Genomic Imaging, University of California, Davis
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     Titi monkeys form strong pair-bonds, characterized by selective preference for their pair-mate, mate-guarding, physiological and behavioral agitation upon separation, and social buffering. Previous research from our lab found adult males had significant changes in central glucose uptake after being paired with a female (Bales et al, 2007). In the current study, we used functional imaging to examine how males viewing their pair-mate in close proximity to a rival male would change central glucose uptake. We hypothesized that this situation would challenge the pair-bond and induce “jealousy” in the males. Animals were injected with 1 mCi/kg of [F-18]-fluorodeoxyglucose, returned to their cage for 30 min of conscious uptake, placed under anesthesia, and then scanned for 1 hour on a microPET P4 primate scanner. Positron emission tomography was co-registered with structural magnetic resonance imaging. During the uptake period, males had a view of either their pair-mate next to a stranger male or a stranger female next to a stranger male (control condition). Eight adult male titi monkeys experienced both conditions. Preliminary mixed-models analysis revealed right lateral septum showed higher glucose uptake in the “jealousy” condition compared to control (p=0.055). Lateral septum has been shown to be involved in mate-guarding and mating-induced aggression in monogamous rodents. Hormones prior to injection and behavior during the uptake period were also measured. Funding: NIH HD053555, RR00169, and the Good Nature Institute.