Abstract # 189:

Scheduled for Friday, June 21, 2013 07:00 PM-09:00 PM: Session 21 (SG Foyer ABC) Poster Presentation


RH5-HTTLPR, RHMAOA-LPR AND EARLY TEMPERAMENT PREDICT REPRODUCTIVE SUCCESS IN CAPTIVE MALE RHESUS MACAQUES (MACACA MULATTA)

J. Jin1,2 and J. P. Capitanio1
1California National Primate Research Center, University of California, Davis, CA 95616, USA, 2Department of Psychology, Peking University
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     Dominance rank does not fully explain individual variation in males’ reproductive success (RS) in rhesus monkeys. Because rh5-HTTLPR, rhMAOA-LPR and early temperament affect social competence, we examined whether these factors were related to variation in RS in captive male rhesus monkeys. In a 25-hour BioBehavioral Assessment (BBA) conducted at 3-4 months of age, behavioral responses to a novel environment and temperament were determined for 158 males. Infants’ genotypes were determined using published procedures. RS for each male was quantified as 1) number of offspring for animals that sired any offspring and the likelihood of having no offspring, and 2) age at first reproduction (AFR), fitted by a zero-inflated negative binomial regression and a linear regression respectively, controlling for age, rank and adult sex ratio in the males’ cages. Genotypes and temperaments affected RS. First, males that had more offspring carried the 5- or 6- allele for rhMAOA-LPR and the short allele for rh5-HTTLPR, had lower Day1 and higher Day2 activity, and were more Vigilant as infants (ps<0.05). Second, males that had a higher likelihood of having no offspring carried the 5-allele for rhMAOA-LPR and were also more Vigilant (ps<0.05). Third, males that had earlier AFR had the 6-allele for rhMAOA-LPR and lower Emotionality as infants (ps<0.05). Differential reproductive strategies associated with genotype and temperament variation were highlighted. (Funding: R24RR019970, RR000169, China Scholarship Council).