Abstract # 30:

Scheduled for Thursday, June 20, 2013 12:00 PM-12:15 PM: Session 3 (Las Olas) Oral Presentation


ALOPECIA IN THREE MACAQUE SPECIES HOUSED IN A LABORATORY ENVIRONMENT

R. Kroeker, R. U. Bellanca, G. H. Lee, J. P. Thom and J. M. Worlein
University of Washington, WaNPRC, Box 357330, Seattle, WA 98195, USA
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     Alopecia is a persistent problem in laboratory macaques, and is important to address due to the perceived implication for health and psychological well-being. Alopecia ratings were taken at 4 time points over a 12-month period on all rhesus (N = 321), pigtail (N = 478), and cynomolgus (N = 75) macaques at the Washington National Primate Research Center, housed singly or small indoor caged groups of up to 4 animals. Results were analyzed using chi square and linear regression. There were species differences in alopecia presentation. Pigtails (63-74%) had higher rates than rhesus (43-55%) while cynomolgus had the lowest rates (7-28%; all chi squares > 32, p < .001). Linear regression for pigtails and rhesus revealed that both species had least alopecia in fall (Sept-Oct) and the most in spring (Mar-Apr; beta = .359, p < .001). Adults (4-10 year-olds) had more alopecia than all other age groups (betas < -.296, p < .001). Rhesus females had significantly increased alopecia compared to males, but there was no sex difference for pigtails. Animals of both species who were identified hair pullers had increased alopecia (beta = 0.431 , p < 0.001). These data indicate that species, time and age can impact presentation of alopecia in laboratory housed macaques and that sex differences may be an important predictor of alopecia in rhesus macaques. Supported by NIH grant P51 OD010425 and NIH grant R24OD01180-15.