Abstract # 5862 Poster # 73:

Scheduled for Saturday, September 13, 2014 07:00 PM-09:00 PM: Session 11 (Decatur B) Poster Presentation


SOCIABILITY IS RELATED TO LOWER BASELINE IMMUNE ACTIVITY IN RHESUS MONKEYS (MACACA MULATTA)

J. J. Vandeleest, J. Jin and B. McCowan
University of California-Davis, California National Primate Research Center, One Shields Avenue, Davis, CA 95616, USA
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     The personality trait Sociability has been shown to be related to immune activity in response to infection. Unknown, however, is whether personality characteristics are related to immune activity in healthy, socially living individuals. The current study assessed personality on 55 animals living in a large ½ acre enclosure housing a total of 133 animals at the California National Primate Research Center. Personality was assessed by observing animals in their social groups for 12 10-min focal sessions and then rating each individual on 29 adjectives. Factor analysis of the 24 reliably rated adjectives with direct oblimin rotation yielded a 3 factor personality structure; Sociable, Excitable, and Confident. Immune parameters were assayed from serum collected during a round-up from anesthetized animals and was assayed for cytokines (IL-6, IL-8, TNF-alpha). Multiple regression controlling for relevant demographic variables (i.e. sex and age) as well as the other personality factors indicated that animals that were more Sociable had significantly lower levels of IL-6 (B= -11.02, p < 0.05) and TNF-alpha (B = -85.98, p < 0.05) and a trend indicating lower levels of IL-8 (B = -411.49, p < 0.1). These results suggest that Sociable animals may be less likely to suffer from health conditions associated with greater systemic inflammation at baseline conditions.