Abstract # 7929 Event # 164:

Scheduled for Sunday, August 27, 2017 09:00 AM-09:15 AM: (Grand Ballroom) Oral Presentation


CANDIDATE GENES FOR PERSONALITY IN COMMON MARMOSETS, CALLITHRIX JACCHUS$

A. Weiss2,3, C. Yokoyama4, A. Kawasaki4, C. Takeda4 and M. Inoue-Murayama1
1The University of Edinburgh, Department of Psychology, School of Philosophy, Psychology and Language Sciences, Edinburgh EH8 9JZ, USA, 2The University of Edinburgh, 3Scottish Primate Research Group, 4RIKEN Center for Molecular Imaging Science
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Studies of humans, great apes, and Old World monkeys identified associations between personality traits and genetic polymorphisms. We tested for some of these associations in common marmosets (N=77; 5 females). We assessed personality using the Hominoid Personality Questionnaire and focused on three polymorphisms: length of the microsatellite located in the intron of the arginine vasopressin receptor 1a (AVPR1a) gene and polymorphisms of the A111T and T329C SNPs of the µ-opioid receptor (OPRM1) gene. Principal components analysis on 47 personality items with interrater reliabilities greater than zero yielded three domains: Dominance, Sociability, and Neuroticism. We used unadjusted linear models to test for personality-genotype associations. For Sociability, marmosets possessing the SS genotype of AVPR1a were higher than their LL counterparts, β=0.91, t(1,70)=2.76, p=0.007. For Neuroticism, marmosets possessing the SL or SS AVPR1a genotype were lower than their LL counterparts: β for SL vs. LL test=-1.25, t(1,70)=-4.26, p<0.001; β for SS vs. LL test=-1.11, t(1,70)=-3.61, p<0.001, respectively. Also for Neuroticism, compared to marmosets with the A/A genotype of A111T and the C/C genotype of T329C, marmosets with the T/T genotype were higher and lower in Neuroticism, respectively: β for A111T=0.77, t(1,72)=2.52, p=0.014; β for T329C=-1.08, t(1,72)=-3.07, p=0.003. These findings suggest that the same genes are responsible for personality variation across three families of primates.