Abstract # 13283 Event # 116:

Scheduled for Friday, August 23, 2019 10:15 AM-12:00 PM: (Wisconsin Historical Society Auditorium) Symposium


IT’S YOUR RESOURCE: NATIONAL PRIMATE RESEARCH CENTER BIOMARKER CORE LABS: MEASURING PHYSIOLOGICAL CONDITION OF NON-HUMAN PRIMATES FOR YOUR RESEARCH HTTPS://NPRCRESEARCH.ORG/PRIMATE/BIOMARKERS/BIOMARKERS-WORKING-GROUP.PHP

T. E. Ziegler1, D. W. Erikson3, K. Ethum4, A. Kapoor1,2, J. Yee5, L. Giavedoni6 and R. Grant7
1Wisconsin National Primate Research Center, 1220 Capitol Court, University of Wisconsin-Madison, Madison, Wisconsin 53715, USA, 2University of Wisconsin-Madison, 3Oregon National Primate Research Center, 4Yerkes National Primate Research Center, 5California National Primate Research Center, 6Southwest National Primate Research Center, 7Washington National Primate Research Center
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     The National Primate Research Centers, supported by the National Institute of Health, have developed a consortium of Biomarker Core Units who perform assay analyses for assessing the homeostasis of nonhuman primates (NHPs). These laboratories have cutting-edge instrumentation and innovative methodologies that can benefit all NHP research, and are available to all investigators using nonhuman primates regardless of field of interest. Key features of these services include the ability to provide customized, species-specific assays to obtain high-quality, sensitive and reproducible data from a variety of biofluids (e.g., blood, urine, hair, saliva and feces). Members of the Biomarker Core laboratories will present new and dynamic assays that are of interest to the NHP scientific community and illustrate the use of these assays in nonhuman primates. These include state-of-the-art developments in reproductive and metabolic panels specific for NPHs via mass spectrometry. For example, species specific metabolic hormones such as insulin for marmoset monkeys, assays for cytokines in macaque monkeys, and other critical immunomarkers to determine disease states. The methods used for these analyses are conducted with a high level of rigor and reproducibility using guidelines established by clinical laboratories. Collectively, this symposium will introduce established and new resources available to the NHP scientific community interested in understanding the fundamental physiological condition of their research subjects.